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      產(chǎn)品名稱:

      鈣結(jié)合蛋白Calponin (Basic)抗體

      產(chǎn)品型號(hào):
      產(chǎn)品產(chǎn)地: 中國(guó)大陸
      訪問次數(shù): 1500
      發(fā)布時(shí)間: 2016/3/29 15:37:15
      Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
      thought to be involved in the regulation of smooth muscle contraction.
      鈣結(jié)合蛋白Calponin (Basic)抗體
    Clone 26A11
    7 mL BOND ready-to-use PA0416 P (HIER)
    Antigen Background
    Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
    thought to be involved in the regulation of smooth muscle contraction. The
    expression of basic calponin is reported to be restricted to smooth muscle
    cells and is a marker of the differentiated contractile phenotype of developing
    smooth muscle. Vascular smooth muscle cells convert to a synthetic
    dedifferentiated phenotype when this protein is lost and this is a key stage in
    both atherosclerosis and restenosis of coronary arteries after balloon
    angioplasty. It is thought that basic calponin exerts its effect via the cortical
    actin cytoskeleton and therefore influences proliferation, the transformed
    phenotype and the metastatic potential of tumor cells. Basic calponin mRNA
    is expressed in smooth muscle of prostate, bowel and aorta whereas neutral
    and acidic calponin mRNAs are expressed in non-smooth muscle tissues
    such as heart, placenta, lung, kidney, pancreas, spleen, testis and ovary as
    well as in smooth muscle-containing tissues.


    Breast carcinoma: immunohistochemical staining with BOND ready-to-use Calponin (Basic)
    (26A11) using BOND Polymer Refine Detection.

    更新時(shí)間:2024/11/12 13:40:42


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    標(biāo)簽:鈣結(jié)合蛋白抗體   Calponin   Clone   26A11   

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